Vad betyder rct
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Randomized controlled trial in health sciences – why and how to run a high quality trial
Content of the course
The randomized controlled trial (RCT) is considered as the most rigorous method of determining whether a cause-effect relationship exists between an intervention and outcome. The strength of the RCT lies in the process of randomization that is unique to this type of study design. There are a lot of important considerations before deciding on and initiating a RCT, which will be dealt with in the course.
Aim of the course
The present course will cover topics on how to design and run a RCT in health sciences, different types of trial designs, sample size calculation, choice of outcome, bias, placebo effect and the publication procedure.
Course fee
The course is free of charge for PhD students enrolled at the Faculty of Health Sciences at SDU.
For PhD students enrolled at other Universities that have joined the "Open market agreement" or NorDoc the course fee is:
DKK
EUR
The course fee for other participants is:
DKK
EUR
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Randomized controlled trial
Form of scientific experiment
A randomized controlled trial (or randomized control trial;[2]RCT) is a form of scientific experiment used to control factors not under direct experimental control. Examples of RCTs are clinical trials that compare the effects of drugs, surgical techniques, medical devices, diagnostic procedures, diets or other medical treatments.[3][4]
Participants who enroll in RCTs differ from one another in known and unknown ways that can influence study outcomes, and yet cannot be directly controlled. By randomly allocating participants among compared treatments, an RCT enables statistical control over these influences. Provided it is designed well, conducted properly, and enrolls enough participants, an RCT may achieve sufficient control over these confounding factors to deliver a useful comparison of the treatments studied.
Definition and examples
[edit]An RCT in clinical research typically compares a proposed new treatment against an existing standard of care; these are then termed the 'experimental' and 'control' treatments, respectively. When no such generally accepted treatment
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Randomiserede, kontrollerede studier
Hvad bruger oss videnskabelige undersøgelser til?
Når oss bliver syge, og sygdommen ikke går over af sig selv, har oss behov for behandling. Behandling kan både være data, råd angående levevis, kost, fysioterapi, läkemedel eller andre tiltag.
Men hvordan ved oss, om behandlingen virker, og at den behandling oss får, er den bedste? Dette svar finder oss i videnskabelige undersøgelser.
Der findes mange forskellige metoder til at bedømme, om enstaka bestemt behandling virker, og om den er bedre end anden behandling.
Guldstandarden, som altså er den bedste metode til at afklare disse spørgsmål, er et såkaldt randomiseret, kontrolleret studie.
På engelsk hedder det randomized controlled rättegång, forkortet RCT.
På dansk kalder oss det ofte et lodtrækningsstudie, da lodtrækningen er et vigtigt element i undersøgelsen.
Hvad er et randomiseret, kontrolleret studie?
Lodtrækning
Idéen inom et randomiseret forsøg er, at behandlingen er den eneste væsentlige forskel mellem de to grupper patienter. Deltagerne inom stu